Advanced Platelet-Rich Fibrin (APRF)
Advanced Platelet Fibrin (APRF) is one of the PRP types, an advanced technology that uses blood that is very rich in white blood cells (leukocyte cells), platelets, and fibrin to help wounds heal very fast. APRF is derived from a patient’s own blood.
APRF is very rich in platelets, growth factor cells, and fibrin but doesn’t contain any additives. Fibrin is the key ingredient that facilitates the healing of a wound. APRF is more advanced than PRP because it has 20 times more growth factor cells than PRP.
Benefits of Advanced Platelet-Rich Fibrin
- APRF is used after surgical procedures to facilitate quick healing. It is also used after dental procedures, such as after extraction of teeth from the sockets and dental implants, to accelerate healing and bone and gum formation.
- APRF contains platelets that help to stop bleeding. When you get injured, the body immediately begins the healing process by rushing different cells to the injured site. Platelet cells also rush to the injured site. These cells circulate in the blood and bind together when they detect damaged blood vessels at a wound site. When you get injured, and blood starts coming out of the wound, the platelets cells quickly bind together at the wound site causing a blood clot which stops further bleeding. This causes the wound to heal faster.
- APRF aids in the treatment of periodontal infrabony defects. It protects open dental wounds from the oral environment and guides against infections.
- APRF improves bone regeneration in a maxillary sinus lift procedure and aids in the repair of bone defects.
- It aids in bone grafting by acting as a biological cement to hold the bone particles together.
- APRF aids soft tissue repair. It is used for soft tissue and bone tissue regeneration.
- APRF has been used in many other clinical applications, such as trauma to the skin, sun damage, acne scars, and wrinkles.
Autologous Conditioned Plasma (ACP)
Autologous conditioned plasma (ACP) is also known as platelet-rich plasma. It is a concentration of platelets and growth factors extracted from a patient’s own blood to enhance the body’s natural healing response and accelerate healing.
Platelets contain a large amount of natural proteins which enhances the natural healing response of the body. Platelets and growth factors initiate and accelerate the growth of new tissue in the tendons and ligaments to facilitate the repair of damaged tendons and ligaments.
ACP has been shown to be helpful in treating symptoms of patients with muscle injury, knee arthritis, tendinitis, and other conditions that may cause chronic pain.
Benefits of Autologous Conditioned Plasma
- ACP injections are given in painful areas to offer significant relief from pain.
- ACP promotes healing by stimulating the growth of healthy tissue and facilitating the repair of damaged tissue.
- ACP promotes healing to help eliminate the need for surgery or the use of medications for a long period of time. It leads to a faster healing process after undergoing a surgical procedure.
Autologous Growth Factors (AGF)
Autologous-derived Growth Factors (AGF) are a concentration of growth factors derived from a patient’s blood used for various medical purposes and aesthetic purposes.
Growth factors contain proteins that accelerate the growth of new healthy tissues to facilitate healing. Growth factors play a crucial role in promoting cellular differentiation and division.
Growth factors are contained in the platelets. After a sample of blood is collected from a patient, the blood is spun at high speed in a centrifuge to separate its components. The growth factor is extracted and then injected into the painful area to stimulate tissue growth and regeneration.
Benefits of Autologous Growth Factors
- AGF has been used for many years as an effective treatment for various medical conditions, including to facilitate healing after surgical procedures.
- AGF is used in the cosmetic field to treat various skin concerns and also used to facilitate skin rejuvenation.
Autologous Platelet Gel (APG)
Autologous platelet gel (APG) is a product of PRP types created by combining PRP with thrombin and calcium to form a coagulum. APG promotes soft tissue repair and regeneration. It stimulates regional bone growth within bones.
APG has a very wide range of clinical uses. It contains growth factors and proteins that facilitate the healing of wounds, including surgical and dental surgery wounds. Many healthcare professionals use APG to facilitate the healing of non-healing wounds various surgical and orthopedic surgical wounds.
Benefits of Autologous Platelet Gel
- Autologous Platelet Gel is widely used by medical professionals to facilitate healing of various types of wounds.
Clinical Platelet-Rich Plasma (CPRP)
Clinical Platelet-Rich Plasma (CPRP) is one of the PRP types used for clinical purposes. PRP contains growth factors and proteins that facilitate healing.
It facilitates healing by stimulating cell growth, tissue repair, and tissue regeneration in the area being treated. CPRP is used in clinical settings for the treatment of various medical conditions and injuries.
Injectable Platelet-Rich Fibrin (IPRF)
Platelet-rich fibrin (PRF) is a combination of platelet-rich plasma PRP types and white blood cells. The PRP and white blood cells are extracted from your own blood to form PRF.
It contains growth factors and white blood cells to produce highly effective wound-healing effects. It stops bleeding faster by causing a blood clot.
To harvest PRF, a blood sample is collected and placed in a centrifuge. The centrifuge is spun at a lower speed. The layers of the blood do not separate out distinctly, unlike when the blood is spun at high speed. Hence, some of the white blood cells and stem cells are still found within the platelets layer.
Benefits of Injectable Platelet-Rich Fibrin (IPRF)
- IPRF is injected into a wound site to stop bleeding and facilitate healing.
- IPRF is also used to rejuvenate the skin.
Leukocyte-poor platelet-rich Plasma (LP-PRP)
Leukocyte-poor PRP is one of the PRP types with a leukocyte (white blood cells) concentration that is below baseline.
Leukocyte-rich platelet-rich Plasma (LR-PRP)
Leukocyte-rich PRP is one of the PRP types with a leukocyte (white blood cells) concentration that is above baseline. LR-PRP has more wound-healing effects than LP-PRP due to its increased concentration of leukocytes.
Platelet-derived Factor Concentrate (PFC)
Platelet-derived Factor Concentrate (PFC) is an extension of PRP types that uses noncoagulating platelet-derived factor concentrate to maximize platelet concentration while removing fibrinogen.
Pure Platelet-Rich Plasma (P-PRP)
Pure Platelet Plasma (P-PRP) is a preparation of PRP types without leucocytes (white blood cells) and with low-density fibrin.
Platelet Fibrin Sealant (PFS)
Platelet Fibrin Sealant, also known as platelet fibrin glue, is fibrin gel used in many surgical fields to seal up spaces after surgical excision where there is potential for serious drainage.
Platelet fibrin sealant consists of fibrinogen and thrombin. The thrombin converts fibrinogen into insoluble fibrin when mixed with calcium and factor XIII.
Platelet-Leukocyte Gel (PLG)
The platelet-leukocyte gel contains high concentrations of platelets and leukocytes in combination with thrombin. PLG is applied to surgical sites to stop blood flow and aid healing. It improves the repair of a wound site and speed up healing.
Platelet-Rich Fibrin (PRF)
Platelet-rich fibrin contains white blood cells (leukocyte cells), platelets, and fibrin. It helps to make wounds heal very fast. Fibrin is the main ingredient that facilitates the healing of a wound.
It also causes blood clots in a wound to help stop bleeding. It is used during surgical procedures to facilitate the healing of surgical incisions.
Platelet-Rich Fibrin Matrix (PRFM)
PRFM is a fibrin matrix that consists of platelet cytokines, growth factors, and stem cells. PRFM can be used to promote wound healing, skin rejuvenation, and hair growth. PRFM can also be used as dermal fillers to stimulate collagen production to fill out wrinkles and lines.
Preparation Rich in Growth Factors (PRGF)
Preparation Rich in Growth Factors contains a small volume of plasma with a high concentration of platelets. It is used to accelerate wound healing and the growth of new tissue.
PRGF has the ability to continuously release multiple growth factors to stimulate tissue growth and regeneration.
How is advanced PRF prepared?
A-PRF is derived from a patient’s blood sample. The blood is placed in a centrifuge and spun at a centrifugation speed of 1,300 rpm (200 g) using the time of centrifugation of 14 min.
What does platelet-rich fibrin do?
PRF is used to promote the healing and sealing of wounds. PRF also promotes bone regeneration, graft stabilization, and hemostasis.
What are the components of PRF?
Platelet-rich fibrin (PRF) contains fibrin enriched with platelets, leukocytes, cytokines, and stem cells.
Do Autologous Growth factor injections hurt?
They don’t hurt as numbing agent is usually applied before the injection is given.
Are there alternatives to Autologous Growth Factors?
Yes. There are alternative growth factors from other sources that can sometimes be used in place of Autologous Growth Factors.
Is platelet gel better than PRP?
Platelet gel is more effective than PRP because it contains platelets, thrombin, and calcium which in combination provide better and faster healing than PRP. However, platelet gel has a relatively higher complication rate than PRP.
What is platelet gel made of?
Platelet gel is made of platelets, thrombin, and calcium. They are combined to form a coagulum.
What is platelet gel used for?
It is used for accelerating the healing of various types of wounds, including non-healing and surgical wounds.
Is platelet gel better than PRP?
Platelet gel is more effective in rejuvenating the facial skin, including the periorbital area, than PRP injection. Platelet contains platelets, thrombin, and calcium, while PRP contains only platelets. The addition of thrombin and calcium increases the regenerative and healing effects of platelet gel.
What is better than PRP treatment?
Stem cell therapy is a more advanced treatment to facilitate healing compared to PRP. PRP uses growth factors in the platelets to aid in the healing of wounds. On the other hand, stem cell doesn’t only use growth factors to aid healing; it also initiates cell growth and tissue regeneration.
What do platelets use to heal wounds?
Platelets quickly form a clot that stops wound bleeding. It contains white blood cells, chemokines, and growth factors that facilitate wound healing.
What is the difference between plasma and platelets?
Plasma is the liquid portion of blood that houses the red blood cells, white blood cells, and platelets. When the blood is spun in a centrifuge, the red blood cells and white blood cells are separated from the plasma. The plasma helps the other components of the blood get into other parts of the body for the proper functioning of the body.
Is PRF better than PRP?
PRF has a higher efficiency than PRP. It contains platelets, white blood cells, and stem cells which provide quicker healing effects than PRP. It releases higher growth factors than PRP.
Is PRF safe?
PRF is extremely safe as it contains PRF extracted from your own blood. There are no adverse reactions.
What is the difference between leukocytes and platelets?
Leukocytes are white blood cells. They play a key role in the immune system and help in the healing of wounds and illnesses. Leukocytes also protect the body from infection and diseases. Platelets are also called thrombocytes.
They contain growth factors and proteins that help stimulate the growth of new cells and tissues. They also help to form clots to stop bleeding from injuries or cuts. Leukocytes and platelets are contained in the blood that flows throughout your body, helping to keep you healthy and also accelerate healing.
What is the main function of platelets?
The primary function of platelets is to stop and prevent bleeding. When you get injured or cut your skin, the blood vessel gets damaged, causing bleeding. Immediately, the body sends signals to the platelets.
The Platelets immediately travel to the injured area and clump together to form a clot at the injured area, which helps stop or reduce the bleeding.
What color are platelets?
When a blood sample is spun at high speed in a centrifuge, the blood is separated into white blood cells, red blood cells, platelets, and plasma. The red blood cells are usually at the bottom of the centrifuge, while the platelets and plasma are at the top. Platelets are cloudy-yellowish in color.